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Romac (Roxithromycin)

Romac is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Romac is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss. Romac is available under several brandnames. Romac is not available in the United States. Romac is available in Australia, Israel and New Zealand. Romac has also been tested to possess antimalarial activity. Romac prevents bacteria from growing, by interfering with their protein synthesis. Romac binds to the subunit 50S of the bacterial ribosome, and thus inhibits the synthesis of peptides. Romac has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.

Other names for this medication:
Roxithromycin, Rulide, Biaxsig, Ixor, Makrodex, Nirox, Overal, Remora, Renicin, Romac, Roxithromycine, Rulid,

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Synthesis of functionalized polystyrenes and end-group modifications. Acetylcholine release was initially increased by immobilization stress, then gradually decreased.

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To estimate the incidence and duration of cervical human papillomavirus (HPV)-6, HPV-11, HPV-16, and HPV-18 infections in a population of young American women. The 5-HT1D agonist sumatriptan, which is highly effective in the acute treatment of migraine, inhibits trigemino-vascular activation in animals, although its actions are normally limited to peripheral components of the trigemino-vascular system. This review is centered on recent advances in the understanding of phosphate flow and novel output signals in chemosensory signaling pathways that are involved in cyst formation and biofilms. Prognostic factors in the intellectual development at 7 years of age in children with congenital hypothyroidism. Strong second harmonic generation (SHG) originating from combined second-order Jahn-Teller (SOJT) distortive cations in a new noncentrosymmetric tellurite, InNb(TeO4)2.

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Tuning supramolecular structuring at the nanoscale level: nonstoichiometric soluble complexes in dilute mixed solutions of alginate and lactose-modified chitosan (chitlac). Rat dermal fibroblast migration was negatively correlated to traction, suggesting migration was not the driving force for compaction with these cells, whereas human foreskin fibroblast migration was positively correlated to traction.

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Platelet-activating factor (PAF-acether) induced leukotriene C4 formation and luminol dependent chemiluminescence by human eosinophils. The absolute stereostructures of camelliosides were determined on the basis of chemical and physicochemical evidence, which included the structure revision of the nortriterpene aglycons (camellenodiol and camelledionol). Immunofluorescent microscopy was positive for intracytoplasmic IgG, IgA, kappa and lambda light chains. Methylation sensitivity of restriction enzymes interacting with GATC sites. Monoclonal antibodies against the K13 polysaccharide strongly stimulated phagocytosis, especially of the type 1 piliated bacteria, suggesting a synergistic effect between binding of type 1 pili and the Fc part of the capsular antibodies to the PMNL.

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Three primary and three middle schools were randomly selected from 26 primary and 30 middle candidate schools in Changning District of Shanghai City in China. Recent studies have improved our understanding of the physiological function of Notch signaling pathway and now there is compelling evidence demonstrating that Notch is a key regulator of embryonic development and tissue homeostasis. All preschool and school-aged children in each community were screened for trachoma in February and July 1996 using the World Health Organization method for clinical assessment of trachoma. Clonal cell lines were isolated from rat hepatoma McA-RH7777 to study expression of alpha-fetoprotein (AFP) in these clones. Eight isomeric networks based on equimolar terpolymers were synthesized using group transfer polymerization (GTP) and were characterized in terms of their swelling properties.

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Flavonoids are phenolic compounds of vegetable origin with antioxidant effects. The prospects for clinical application of selective JAK2 inhibitors are discussed. Analysis of the complete genomic sequence of an apparently avirulent strain of avian hepatitis E virus (avian HEV) identified major genetic differences compared with the prototype pathogenic strain of avian HEV. This is a potentially confusing finding in the patient with renal trauma.

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The General Practice Research Database was used to compare the incidence of common comorbid conditions (International Classification for Disease-10 codes). Numerous experimental findings have proven the feasibility, safety, and efficiency of MSC therapy for cardiac regeneration. Palliative care is a multidisciplinary approach that focuses on the improvement of quality of life (QOL) of patients as well as their families. Most of the hybridizing genomic fragments corresponded to complete cDNA sequences, and it is estimated that each of the two classes is encoded by about 10 genes. Here we report a novel role of vimentin IF and plectin in metastasis.

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Lymphocyte migration into inflammatory sites involves a change from a spherical, non-motile phenotype to an irregular, constantly shape-changing, motile phenotype. However, our data do not allow to rule out that the interferon producing cell may be an immature macrophage or an immature T cell. Sulerythrin, the smallest member of the rubrerythrin family, from a strictly aerobic and thermoacidophilic archaeon, Sulfolobus tokodaii strain 7.

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The inhibitory activity of NifL is restored under conditions of excess combined nitrogen through the binding of the signal transduction protein Av GlnK to the carboxyl-terminal domain of NifL. This study examines TRAF1 and LMP1 expression in EBV associated lymphoproliferations.

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Although we could not find good anti-HIV agents in this study, findings of some anticancer activity in this series will allow this class of nucleosides to be the new template for the development of new anticancer agents (Fig. The binding of ORC2 to chromatin from terminally differentiated cells. The ISCS demonstrated preliminary reliability and validity in this sample. Analysis of the quinolone-resistance determining region of the gyrA gene and the analogous region of the parC gene in Ureaplasma parvum and Ureaplasma urealyticum detected in first-void urine of men with non-gonococcal urethritis.

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End-of-life expenditures by Ohio Medicaid beneficiaries dying of cancer. A new strategy in drug design of Chinese medicine: theory, method and techniques. However, the effect of paeonol on alcoholic liver injury remains obscure. The pattern of surface density and distribution of Langerhans Cells (LC) in the Swiss Webster (SW) albino mouse is reported. Although well tolerated, vinblastine sulfate given by this method has no activity in this malignancy.

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Early developmental processes in activated, unfertilized eggs were investigated and compared with those in fertilized eggs. The DATS-mediated accumulation of cyclin B1 and hyperphosphorylation of securin, Cdc20, and Cdh1 were partially but markedly attenuated by knockdown of Chk1 or ATR protein. These drugs have demonstrated improved progression-free survival as well as potentially improved overall survival for patients with metastatic disease. Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.

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