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Isosorbide
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Isosorbide

Dose-dependent headache response and dilatation of limb and extracranial arteries after three doses of 5-Isosorbide-mononitrate. We performed a population-based pharmaco-epidemiological case-control study with fracture in 2000 as outcome and use of nitrates (Isosorbide mononitrate, Isosorbide dinitrate, and nitroglycerin) during the previous 5 years as exposure variable.

Other names for this medication:
Isosorbide, Isordil,

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Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Isosorbide is in a class of medications called vasodilators. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen.

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Univariate analyses were used to explore trends over time in drug prescriptions and patient characteristics. This happens because the substance absorbs the ultrasound waves.

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Radical lymphadenectomy for melanoma is associated with significant morbidity. They are: the place where the anterior part of the interventricular septum passes into the anterior wall of the left ventricle, the right edge of the papillary muscle, the left edge of the anterior papillary muscle, the left edge of the posterior papillary muscle, the right edge of the posterior papillary muscle, the place where the posterior part of the interventricular septum passes into the posterior wall of the left ventricle. The EAGLE has curved blades that create a 6-mm grasping surface that is the same diameter as the anvil stem and is covered with tungsten carbide tips. The most often used formula is the one proposed by Crockroft and Gault in 1976.

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The progress of saccharification reactions and production of DEH were verified by thin layer chromatography and gas chromatography-mass spectrometry, respectively. The defense mechanism and its weakening: significance of antigen mutation--antigenic shift and drift of Plasmodium

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In a long-term study discontinuous extracorporeal blood irradiation (ECIB) was applied to a goat using a 500 Ci-137 Caesium source. Evaluations included measures of subjective feelings of intoxication and body sway, and changes in cortisol, ACTH and prolactin. Our group has recently developed a viral animal model of FHF by means of the inoculation of rabbits with the virus of the rabbit hemorrhagic disease. Sequence analysis revealed that the SmfY was a multidrug efflux pump of the MF (Major Facilitator) superfamily transporters.

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We conclude that Tpl2 is an important signal transducer for TLR activation of gene expression in KCs and HSCs by the ERK pathway and that suppression of its catalytic activity may be a route toward suppressing fibrosis caused by hepatocellular injuries. A randomized controlled trial in older women with unexplained infertility to compare treatment initiated with two cycles of controlled ovarian hyperstimulation/IUI versus immediate IVF demonstrated superior pregnancy rates with fewer treatment cycles in the immediate IVF group.

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Mechanism of action, spectrum of activity, pharmacokinetics, drug interactions, adverse reactions and therapeutic use. A porcine model of neurological decompression illness (DCI) and its treatment is described.

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The practical synthesis of vitamin D analogs: a challenge for process research. Patellar tracking was evaluated in vivo and noninvasively with corroboration using in vivo fluoroscopy and in vitro cadaver measurements.

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In addition, complete blood counts and biochemical profiles were monitored for Dogs 2 and 3 every 7 days for 30 days. Chemical analysis of these glycopeptides and their parent macromolecules revealed that the oligosaccharide residues are attached to threonine, serine and proline residues of the protein chains. We also demonstrated that HGF stimulates autophosphorylation of its receptor, followed by activation of the Ras-MAP (mitogen-activated peptide) kinase cascade.

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The liver takes up and/or retains mainly saturated fatty acids during mucositis. Comparison of cytoplasmic RNA species from rat liver and Morris hepatoma 5123D. Characterisation and quantification of angiogenesis in beta-tricalcium phosphate implants by immunohistochemistry and transmission electron microscopy. Clomiphene citrate treatment (250 to 750 mg per cycle) decreased both endometrial estradiol and progesterone receptor concentrations.

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The analysis is based on the general model of continuous medium with mechanochemical reactions. Dissociation of DNA from histone by reaction of anti-cancer drug cis-diamminedichloroplatinum(II) with DNA-histone complexes used as cellular model. An abnormal fetal karyotype, containing a del 16(q21-qter) as an extra chromosome, was diagnosed in all 14 metaphases examined in a sample of chorionic villous biopsy material.

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Studies were made of the ultracytochemical changes in the cell membrane and microfilaments of colonic epithelial cells during tumorigenesis induced by 1,2-dimethylhydrazine (DMH) in mice fed a high fat diet. We have developed a simple method for guidewire exchange of the femoral venous ECMO cannula to a working catheter for intravascular ultrasound (IVUS) IVC filter placement, and describe the specific methodology. Some patients with permanent azoospermia after chemotherapy can be successfully treated by TESE-ICSI. The protective effects of tea catechins on the injury of cerebral ischemia and reperfusion in rats

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An early infusion of dobutamine at a fixed dose of 5 microg/kg per min during the first 72 h of severe sepsis does not influence gastric DeltaCO2. The clinical diagnostic criteria are advanced age, morphology of the intracerebral hematomas, occurrence of several episodes of intracerebral haemorrhages and presence of dementia. Low nanogram range quantitation of diglycerides and ceramide by high-performance liquid chromatography.

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However, these tracers present different properties and have to be chosen carefully. Valuable discussions have been held during the last decade between specialists and primary care physicians to define the clinical elements that should be included in bedside examinations carried out by general practitioners. This relies on the absorption of iodine by starch to produce a blue color that can be quantified colorimetrically. However, a small but significant risk elevation is present among men smokers.

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These observations emphasize the need for an improvement of our understanding of the taxonomy and epidemiology of atypical A. Upregulation of FKN and its receptor was significantly correlated with the trafficking of mononuclear cells which play an important role in acute allograft rejection. The algogenic-induced nociceptive flexion test in mice: studies on sensitivity of the test and stress on animals.

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The expression of MMP-1 and TIMP-1 was enhanced, but the expression of a-SMA was decreased by (60)Co gamma rays. Western blot analysis revealed that neuronal-specific enolase, a marker of the neuronal lineage, was increased by AR knockdown in LNCaP cells.

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The pH dependence of log K(m), log k(cat), and log(k(cat)/K(m)) of both WT and H178A EcMetAP-I were also obtained and are identical, within error, for H178A and WT EcMetAP-I. Our study adds prospective evidence to the role of early initiation of smoking and alcohol drinking as relevant markers of lower bone mineral density in late adolescence. This is the first study to externally validate scores developed for prevalent undiagnosed disease in this age group using both OGTT and HbA1c.

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However, there was a trend towards a lower viscosity after longer exposure to the gastric juices. The evidence for an against a central site of action of beta-agonists with respect to their effect on serotonergic systems is discussed. From a total of 1205 papers identified in database searches following Cochrane and PRISMA Group guidelines, 18 were included for review. Authors have examined correlations between total body water, extracellular fluid, and body cell mass and the drug volume of distribution or clearance and the elimination rate constant. Additionally, leptin administration upregulated the extracellular signal-regulated kinase1/2 (ERK1/2) phosphorylation.

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Anxiolytic and neuroleptics have also been tried, but the results are inconsistent. Computed tomography characterization of neuroendocrine tumors of the thymus can aid identification and treatment. In this study, X-ray absorption spectroscopy (XAS) and X-ray fluorescence microscopy (XFM) have been used to investigate the speciation and distribution of Se and Cu in vivo. Dural arteriovenous shunts are abnormal arteriovenous communications within the dura.

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Principle demonstration of nutrient delivery system in a space vegetable planting prototype facility Comparative analysis of gene structures and enzyme functions highlights the molecular evolution of these diTPSs as conserved between gymnosperms and angiosperms. Variety of audiologic manifestations in patients with superior semicircular canal dehiscence. The mean GnT-V activity in the sera of patients with HCC increased in accordance with the degree of tumor invasion. A 29-year-old woman with primary infertility caused by bilateral isthmical tubal block was operated upon with bilateral cornual resection and tubal implantation.

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Integrating a hospital-based hotel into admissions administration. Histologically, intra- and extracellular PAS-positive hyaline globules were observed in the tumor.

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Furthermore, greater distances from the source had higher relative dose differences and the effect can be justified due to the change in photon spectrum (softening or hardening) as photons traverse the phantom material. The subgroup analysis suggests that antiplatelet therapy may be needed in diabetic patients with a high baPWV for prevention of ischemic stroke. Increase in tissue glycogen content indicates the effect of the drug on the uptake of glucose by the peripheral tissues to reduce insulin resistance of NIDDM.

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The dispersion of time to the maximal longitudinal strain (LS) of left atrial segments facilitated prediction of SR maintenance. We have developed a microscopic analyzing system for studying in vivo hepatic microcirculation, and measured the sinusoidal erythrocyte flow velocity simultaneously in the various sinusoids.

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Envelopes of large-cell variant Coxiella burnetii, the agent of Q fever, were the starting material for purification of an outer membrane protein (OMP) oligomer with aggregate molecular mass of approximately 2 x 10(4) kDa. The sensitivity of these trends to variations in proximate determinants such as the marriage pattern and the duration of lactational amenorrhea, as well as in the discontinuation rate and the method mix, are examined. Thirty-nine practices accruing five or more patients per practice were included in the analyses.

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One day of food restriction does not result in an increase in subsequent daily food intake in humans. Identification and somatotopic organization of nuclei projecting via the dorsolateral funiculus in rats: a retrograde tracing study using HRP slow-release gels. IVUS and angioscopy might be effective for detecting and evaluating the infarct-related vulnerable plaque and for making the therapeutic strategy when percutaneous coronary interventions are performed. The output coupler, herein described, utilizes a frustrated total internal reflection configuration and is fabricated of fused silica with an air gap 0.483 micro in thickness as the critically controlled element. There is growing concern from multiple studies that radiation from repeated CT scans could induce malignancies later in life.

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Lysozyme and lipid deposition on silicone hydrogel contact lens materials. Culiseta melanura (Diptera: Culicidae): population structure and nectar feeding in a freshwater swamp and surrounding areas in southeastern Massachusetts, USA. The study tested the hypotheses that two common process factors (internal locus of control and sociability) and two unique factors (spirituality and installation of hope) mediate the effects of 12-step group affiliation on drug/alcohol abstinence and health promoting behavior.

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Resonance Rayleigh scattering technology as a new method for the determination of the inclusion constant of beta-cyclodextrin. This has rarely been reported, and no studies have compared it with other cases of rhabdomyolysis. This case demonstrates the existence at an earlier developmental level of perverse qualities which have previously been identified in adults. These data suggest that adolescence constitutes an additional period when the effects of developmental programming may modify mental health trajectories.

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Later in life, patients display different types of afebrile seizures including myoclonic seizures. Negatively charged lipids accelerated the binding of lacticin Q on the membranes and the resulting pore formation. In the standard plant transformation practice, transgene copy number is often inversely correlated with transgene expression.

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N-Acetylcysteine (NAC) is an artificial precursor of GSH which both increases GSH levels and acts as OFR scavenger. Part of the toxin is degraded by the proteasome, but a fraction of the ricin avoids degradation and inhibits protein synthesis by inactivating ribosomes, ultimately leading to cell death. These findings suggested that increased intracellular synthesis dut to enzyme superactivity underlay purine nucleotide and uric acid overproduction in these patients.

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