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Escitalopram is the S-enantiomer of the racemic compound citalopram, a selective serotonin reuptake inhibitor (SSRI) widely used for the treatment of depression. This review describes the current body of pharmacologic and clinical evidence supporting the use of Escitalopram for the treatment of depression and anxiety. Preclinical studies have confirmed that it is primarily this molecule that provides the inhibition of serotonin reuptake responsible for the antidepressant effect of citalopram, with minimal-to-nonexistent affinity for other receptor sites. Clinical trials of Escitalopram in depressed patients indicate that Escitalopram, 10 mg/day, is as effective as 40 mg/day of its parent compound, citalopram, with an excellent safety and tolerability profile. Because of its increased selectivity, Escitalopram represents a refinement in SSRI therapy for symptoms of depression and anxiety. This article also explores the implications of a more selective SSRI on the management of depressed patients in the primary care clinical practice.

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Escitalopram, Lexapro, Aramix, Celtium, Cipralex, Citoles, Ectiban, Entact, Esertia, Esipram, Esita, Eslorex, Esram, Gaudium, Lexamil, Lextor, Losiram, Losita, Neozentius, Nexcital, Seroplex, Sipralexa, Tiopram,

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Escitalopram is used to treat depression and anxiety. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Escitalopram belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRI). It may improve your energy level and feelings of well-being and decrease nervousness. OTHER This section contains uses of this drug that are not listed in the approved US professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to treat other mental/mood disorders (such as obsessive-compulsive disorder, panic disorder) and hot flashes that occur with menopause.

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This results in bilateral synchrony of spikes in the CGC-axons in both the buccal and the lip nerves. We investigated the expression of TREM-2 in the intestinal lamina propria and its role in the development of colonic inflammation. The clinical and radiographic results at six months are presented and the operative technique used in this case of pseudodislocation of sternoclavicular joint is discussed and compared to those previously published. A single-center, open-label, 3-period, crossover drug interaction study was performed with 22 healthy volunteers. Findings pertaining to aldosterone production differed from those reported following acute administration of Teprotide wherein a decrease in the production of serum aldosterone and an increase in plasma renin activity was observed.

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The major envelope protein, GP5, of a European porcine reproductive and respiratory syndrome virus contains a neutralization epitope in its N-terminal ectodomain. The major thrust of the worldwide effort on the disease entity cystic fibrosis is concerned with genetic, diagnostic and therapeutical questions and detection of the primary defect.

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Normal ranges were calculated from regression analysis of these relationships. Intravenous LPS (3 mg/kg dissolved in sterilized saline) was given to rats 12 h after food removal. Folate antagonists and direct-acting inhibitors of thymidylate synthase are potent genotoxic antimetabolites. There are reports of extension of intracranial schwannomas laterally to fill the middle ear and meatus, but in reviewing the English literature, we have found only one report of a primary external canal schwannoma. More specifically, we study whether it is plausible that people strategically look for a particular type of feature co-occurrence that can be represented in terms of rectangular patterns of 1s and 0s in a binary feature by exemplar matrix.

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Since no independent mobility could be detected it is suggested that the (charged) chromophoric group is folded against the protein surface. The results of several clinical trials in MS indicate that suppression of the immune-mediated inflammation may decrease the relapse rate in MS, but not stop the progressive loss of neurologic function.

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That is, even when search imposes no immediate costs, people adopt the same pattern manifest in costly search: early exploration followed by later exploitation. Cell transplants and treatments that increase cAMP and neurotrophins stimulate motor and sensory axons to cross glial scars and to grow long distances in white matter. A soluble factor (less than 4000 Da) from chick spinal cord blocks slow hyperpolarizing afterpotentials in cultured rat muscle cells.

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Here, we describe the application of real-time and conventional PCR-based methods for confirmation of presumptive Listeria isolates. Diversification in the Centaurea group mainly took place during the Pliocene and Pleistocene. These results are compared with previous studies of platelet serotonin transport in clinically depressed patients and in physostigmine-induced depression.

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All the patients were successfully operated, and postoperative courses were uneventful. This is accomplished by shifting the capsule to buttress the glenoid labrum. The MTDs/LD50s of Taxol, paclitaxel-loaded LNCs and blank LNCs were 12/19.5, 96/216 and above 288/288 mg/kg, respectively. Karyotypes of the 5-azacytidine-sensitive and -resistant line of AKR mouse leukemia. The results demonstrate a causal relationship between oxygen supply and energy state in contracting as well as recovering skeletal muscles.

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From these results, it was concluded that the lipid peroxidation due to ferric ion chelated with chinoform incorporated into the membrane of nerve tissues is the most important step in induction of the neuropathy. Rethrombosis limits the efficacy of coronary thrombolysis and may result from surface-associated thrombin, de-novo prothrombin activation, or both. Morphologically the tubules are similar to the epithelial component seen in pulmonary blastoma, but the tumor lacks the sarcomatous areas integral to the concept of blastoma.

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Medical Subject Headings (MeSH): screening, mammography, cervical cancer, Pap, breast exam. Decreased apolipoprotein A5 is implicated in insulin resistance-related hypertriglyceridemia in obesity.

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The cartilage endplate was worn out at the early stage and calcified in situ later. Overexpression as well as downregulation correlates with the generation of multinucleate cells.

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Protein fractions were analyzed using acetate cellulose electrophoresis. This correlation was not seen in control or insulin-treated rats. The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells. Gefitinib (IRESSA) with vinorelbine or vinorelbine/cisplatin for chemotherapy-naive non-small cell lung cancer patients.

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The amino-terminal domain of rabbit secretory component is responsible for noncovalent binding to immunoglobulin A dimers. Clinical trials of live recombinant BCG or attenuated MTB vaccines may be considered in latently infected adults, with or without INH pretreatment ( identifier: NCT01119521). Recent mechanistic studies have shown that ROS production by the fluorophore and a latent lytic ability of CPPs act in synergy to elicit photolysis.

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Synovial fluid from patients with rheumatoid arthritis contains a unique inhibitor of interleukin 1 alpha. Decreased expression of CD82/KAI1 and E-cad was closely related to cellular differentiation, pTNM stages, invasion and metastasis. Multiple affinity protein profiling (MAPPing) that combines 2-D immunoaffinity chromatography, enzymatic digestion of the isolated proteins, and identification by MS/MS, may facilitate the identification of these so far unknown patient antibodies.

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Diagnosis may be made safely in the presence of a characteristic collateral history. Treatment with MK-571, a leukotriene D4 inhibitor, effectively attenuates airway hypersensitivity, pulmonary inflammatory response, and lung and kidney injury. Use of comparative proteomics to identify key proteins related to hepatic lipid metabolism in broiler chickens: evidence accounting for differential fat deposition between strains. Likewise, participants in rooms with high temperature regarded criminals to be more hot-headed than participants in rooms with low temperature: They were more likely to attribute impulsive crimes. Policy documents, public financial and budget documents, and related papers were reviewed.

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Furthermore, staining of alpha-tubulin subunits demonstrated that embryonic tubulin organisation was altered. These immunoassays have several advantages that include high sensitivity as well as being rapid and facile for determination of the triterpene glycosides in C. Cell displacement on the radius depends solely upon cell production and the acceleration of a cell through location i equals the cell production rate there. The mechanical properties, color and transparency of glass-ceramics are highly dependent on the ceramming temperature and/or amount of the crystal phase in the glass matrix.

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Our results suggest that multiple oncogene or tumour suppressor gene mutations may play an important role during malignant transformation in conventional giant-cell tumours. Superstring theory, a consistent theory of quantum gravity, provides a possible solution to the paradox if evaporating black holes can actually be described in terms of standard quantum mechanical systems, as conjectured from the theory. Extreme genome reduction in Buchnera spp.: toward the minimal genome needed for symbiotic life. Because AP-1 decoy transfection in vivo dramatically prevented neointimal thickening in balloon-injured arteries, AP-1 may be a useful molecular target for gene therapy to reduce restenosis.

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Beside exogenous ligands, an increasing list of endogenous ligands has recently been described. Advantages offered over traditional methods include cost-effectiveness, controllability, low volume, high resolution, and sensitivity. An open, self-controlled study on the efficacy of topical indoxacarb for eliminating fleas and clinical signs of flea-allergy dermatitis in client-owned dogs in Queensland, Australia. Immune suppression associated with morbillivirus infections may influence the mortality rate by allowing secondary bacterial infections that are lethal to the host to flourish.

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We further show that MgrB homologs from Salmonella typhimurium and Yersinia pestis also repress PhoP-regulated transcription in these organisms. The prevailing views on the role of public health professionals refer to professionals in the academic world, without taking into account the fact that many public health professionals are government employees. The clinical importance of asymptomatic deep venous thrombosis in elective hip surgery is not clearly known.

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Serum S100beta: a noninvasive marker of blood-brain barrier function and brain lesions. Proper functioning of biological systems that respond to periodic signals requires the ability to synchronize with the periodic excitation.

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It was not possible to demonstrate antigenic cross-reactivity between OMC-1 and endogenous type C viruses of baboons. Clinical and 30 MR findings of 29 patients with EBV encephalitis or encephalomyelitis were retrospectively reviewed.

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Dependence of the therapeutic effectiveness of interleukin-1beta on the time of the drug administration after irradiation of mice Transfections of wild-type or mutant SORT1 plasmids in HeLa T-REx cells and the use of siRNA were used to study the effect of sortilin on the number of cell-surface LDL receptors and on the binding and internalization of LDL. Localization of NTPDase1/CD39 in normal and transformed human pancreas.

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It was seemed that epigenetic changes could be of the earliest events observed during cancer development, making them excellent targets for chemoprevention. Introduction of a nurse-led management program significantly improved detection of nephropathy.

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This review focuses upon results of research to date, which have demonstrated that both cell-mediated and cell-free components of the innate immune system are involved in these processes. It is of interest to correlate the locations of cells projecting to the ASs-MSs area with the pathways terminating in thalamic regions. In normal cells, STAT3 activation is tightly controlled to prevent dysregulated gene transcription, whereas constitutively activated STAT3 plays an important role in tumorigenesis through the upregulation of genes involved in anti-apoptosis, proliferation and angiogenesis.

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Placental nutrient transport is affected by pregnancy rank in sheep. To estimate probabilities of alcohol high-risk drinking, alcohol abuse and alcohol dependence on grounds of smoking-behaviour related variables and single nicotine dependence criteria.

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The role of the family history in preventive medicine: an introduction for medical librarians. Embedding ITZ NP in inhalable microparticles is a very effective method to produce DPI formulations with optimal aerodynamic properties and enhanced ITZ solubility. Second, the type I IFN program initiated in DRG neurons induces less cell death than in mitotic cells.

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Metformin protects against seizures, learning and memory impairments and oxidative damage induced by pentylenetetrazole-induced kindling in mice. This suggests that the molecular determinants of ligand recognition and reactivity are highly conserved across species. Interestingly, cadmium significantly decreased the amount of TGF-beta1 in the conditioned media.

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We also find that modernization and pathogen prevalence theories do not fit the data. Hcy can increase intestinal permeability and aggravate inflammatory damage in rats with TNBS-induced colitis, the underlying mechanisms of which may be attributed to its effects of promoting the expression of MMP-2 and MMP-9, leading to injury of the intestinal barrier. The possible role of the accessory glands based on their histochemical analysis has been speculated. To determine the serum levels of eotaxin, IL-13 and total IgE (TIgE) in asthmatic children during the acute and clinical remission periods, as well as the changes in pulmonary function to determine their roles, relationships and clinical significance during asthma exacerbation. As both protein kinase C (PKC)alpha and beta are involved in VEGF-induced COX-2 expression and CREB activation, we investigated which isoform(s) of PKC was affected by RSG.

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Furthermore, the possibility that the condition might also be a joint disease related to the group of rheumatic diseases called spondyloarthropathies should be considered. The prevalence of Clostridium difficile infection in pediatric and adult patients with inflammatory bowel disease. Soybean glycinin belongs to the 11S globulin family and consists of five kinds of subunits. The effects of total airway infection versus upper airway infection on sleep were tested in two groups of mice using the same strain of virus (H1N1). Increased usage of the Internet has given rise to a new challenge to marriages: That of online infidelity, which is perceived to be as traumatic as actual infidelity.

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The detection limit for vitamin B(1) was 0.0053 mg L(-1) for the accumulation time 120s. The peristomal area of each patient was evaluated on a daily basis for one week after PEG. The obtained solution of the objective function can generate more stable results than the l0 penalty and smaller reconstruction errors than the l1 penalty. Human monoclonal anti-I and anti-i antibodies, reactive with known carbohydrate sequences, have been used as reagents to quantitate (by radioimmunoassay) and visualize (by immunofluorescence) the expression of the various blood group I and i antigenic determinants in a variety of cultured cell lines commonly used in laboratory investigations. The application of this technique, for the demonstration of nucleic acids in different tissues, is illustrated.

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Effects of Astragalus polysaccharides and astragalosides on the phagocytosis of Mycobacterium tuberculosis by macrophages. A randomized controlled trial of exercise to improve mobility and function after elective knee arthroplasty. Biophysical properties of unusual phospholipids and sterols from marine invertebrates.

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In primary care publications there is great diversity in both research areas such as in journals where published. Depression of the somatotropic cells in the bovine pituitary gland due to application of recombinant bovine somatotropin--an immunohistochemical and morphometric study. To know the association between burnout, its dimensions and sociodemographic-laboral variables.

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The former discloses electrostatic interaction, hydrophobic interaction, and hydrogen bonding in the copolymer/DNA system, whereas the latter indicates that these graft copolymers can bind DNA via the electrostatic and classical intercalation modes. A subgroup of patients benefiting most from robot-assisted therapy (RT) has not yet been described.

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Standardbreds may be more likely to have abnormal gas exchange than Thoroughbreds. The telephone was found to be an important means of communication for rural practitioners, primarily in terms of organising referrals. We described whole cell and cell-free systems capable of inserting into membranes cytochrome P-450 and epoxide hydratase made under the direction of rat liver RNA.

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Exposure to UV light for short periods was non-toxic to primary macrophages and red blood cells, but produced extensive killing of CHV79 cells. Proton-induced cross-sections of nuclear reactions on lead up to 37 MeV. An adequate fixation angle is necessary to avoid airway obstruction after an occipitocervical fusion, even for short upper cervical fusions, especially in patients with rheumatoid arthritis. The sine wave protocol: decrease movement time without increasing errors.

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These case studies exemplify the combined data analysis proposed and further support its validity. Our study introduced an alternative way to utilize this worthless residue using biotechnological knowledge. A 14-year retrospective maternal report of alcohol consumption in pregnancy predicts pregnancy and teen outcomes.

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escitalopram drug action mechanism 2019-12-28

Denosumab in a dose of 60 mg every six months does not seem to delay fracture-healing or contribute to other complications, even when it is administered at or near the time of the fracture. Pyrethroid exposure following david tensen skillchoice australia indoor treatments with a dog flea powder

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Eight hundred sixteen patients who were consecutively diagnosed as having melanoma and treated at 11 participating centers. ATP release from the carotid bodies seborrheic dermatitis treatment ketoconazole 200 of DBA/2J and A/J inbred mouse strains. He was found to have an atypical lesion of the urinary bladder on cystoscopic examination. Microsatellite mutation in the maternally/paternally transmitted D18S51 locus: two cases of allele mismatch in the child.

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Most vitreous samples from patients without intraocular neovascularization lacked similar stimulatory activity. Identification, characterization, and expression of a novel alpha-tropomyosin isoform in cardiac tissues in developing chicken. A comparison of plaque quantification by two- and three-dimensional ultrasound. The higher doses (0.05-5.0 micrograms/mouse) inhibited the histaloc tablets walmart development of tolerance.

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Early onset substance use, adolescent antisocial behaviors and lifetime alcohol and illicit drug use were used as criterion variables. The aim of this study was to clarify the significance of a Q wave in lead negative aVR (-aVR) in anterior wall acute myocardial infarction (AMI). Effects of oestrogen-induced hyperprolactinemia on the rat prostate. Kissing or overlapping instrumentation increases load to failure and cefoprox syrup restaurant creates a more biomechanically stable construct than gapped implants. Patients with postoperative complications exhibit less improvement in OAB symptoms.

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The obtained equation provides pepticum 20 mg a new tool to analyze optical microscopy data and, thus, to measure the adhesion energy per area by analyzing the geometry of the adhering vesicle. Mutual confrontation of existing theoretical models with reliable data obtained under comparable conditions can aid gradual mapping of this hitherto badly organized and understood discipline of biology. Molecular cloning and characterization of cDNAs encoding heterotrimeric G protein alpha and beta subunits from potato (Solanum tuberosum L.). Two-hundred and fifty-nine patients undergoing epidural anesthesia were randomly allocated into six groups. An application of reconfigurable technologies for non-invasive fetal heart rate extraction.

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A substantial number of patients at risk for thromboembolic events are not anticoagulated, and further studies are needed to determine how many of these patients are candidates for espironolactona 25 mg promethazine anticoagulation. Dermatologists and Paediatricians play a essential role in this educational work. In the 1960s, studies on adult neurogenesis have been hampered by the lack of established phenotypic markers. dFdCDP exhibits the cytotoxic effect by inactivating ribonucleotide reductase larger subunit 1 (RRM1), which is a rate limiting enzyme for de novo DNA synthesis. In this review, we report the different strategies to access monofluorocyclopropanes and highlight some of their attractive biological applications.

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Immune-based agents represent a new approach to the treatment of HIV infection. Recommendations to avoid this complication include shortening of the forearm at the osteotomy site and maclar $500 used car for sale the release of unyielding soft tissue restraints. In contrast, mutants Cys98Ser, Cys98Ala, Cys179Ser, and Cys179Ala showed no high affinity TRH binding. The separation of management from ownership is well advanced with a management committee being in effective control. DSPP protein is necessary for proper dentin formation, and understanding its structure and function should yield important insights into how dentin forms and biomineralization is controlled.

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Parenteral fish oil as monotherapy prevents essential fatty acid deficiency in parenteral nutrition-dependent patients. It was shown that smoking cues elicit craving due mainly to a generated expectation of the occurrence of smoking and less due to salience or long history of associative learning. References and general recommendations for applying this model to special populations are provided. All fracture/dislocations, with the exception of a scapula fracture, anterior dislocation motrin spanje vs nederland of a thumb interphalangeal joint, and a fractured coronoid process of the ulna, required open reduction with internal fixation. Stable suppression of mutant BRAF(V600E) or both wild-type and mutant BRAF(V600E) by RNA interference in melanoma cells resulted in significantly decreased HIF-1alpha expression.

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The type of surgical intervention for trimetazidine bcs classification of diclofenac isolated sagittal synostosis impacts long-term neuropsychological outcomes. Examination of 116 children with cystic cystitis revealed it to be associated with urinary tract anomalies, especially vesicoureteral reflux.

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Neuron Specific Enolase (NSE) is released following central nervous system (CNS) distress. In the development of chronic kidney allograft rejection acute rejection (AR) is the single most important risk factor. Occipital gamma-augmentation enhanced during naming of unambiguous images can be explained by visual processing of stimuli with grepid medicine cabinets richer detail. The objective of this study was to evaluate the importance of serum ferritin levels and other indicators of organic iron as possible risk factors or markers in coronary artery disease.

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The FCRN is a single hidden layer network with a Gaussian-like sech activation function in the hidden layer and an exponential activation function in the output layer. Effect of the glycemic index of the diet on weight loss, modulation of satiety, inflammation, and other metabolic risk factors: a randomized controlled trial. Many other proteins also assemble around CENP-A nucleosomes in interphase nuclei dose of acyclovir for prophylaxis define to form the interphase centromere complex (ICEN). Serum IL-6 levels were significantly increased in the high one-lung ventilation ratio and long-term one-lung ventilation groups. Fifty-one patients with acute renal failure were included and evaluated clinically with regard to the etiology of the renal failure, whether underlying chronic renal failure was present, and if dialysis was required.

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